About Us

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Metalloenzymes catalyze a broad range of biological transformations important for cofactor biosynthesis, antibiotic production, and primary metabolism. Visualizing their catalytic processes in real-time, however, is technically challenging and our understanding of this vast mechanistic landscape remains limited.

Our lab focuses on the development and application of time-resolved physical methods to elucidate the mechanisms of metal-containing enzymes important for human health and medicine. In particular, we interrogate the concerted modulation of electronic properties and structural dynamics which facilitate metallocofactor function using carefully tailored spectroscopic and crystallographic experiments.

 

Working at the interface of physics, chemistry and biology, we welcome members from all backgrounds and life experiences.

 

 

Unfortunately, we are cannot accommodate new undergraduate scholars at this time. Please check back again later.

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News

Lab News

  • 7/5/23: Check out Kendra’s work in ACS Chem Biol. ! Robust Chemoenzymatic Synthesis of the Keratinimicin Aglycone Facilitated by the Structure and Selectivity of OxyB. ACS Chem. Biol. 2023, 18, 1472-1479.
  • 6/26/23: And the first ever Davis Lab PhD goes to… TAMRA BLUE LAHOM!!! Keep an eye out for this rising star as she continues on to her assistant professor position at Carleton College and postdoc position in the Booker Lab at Penn State. We will miss you!!! <3
  • Twitter stopped working on this website so check out current news as of Summer 2023 here! 🙂